An optimization of protocol for mixed chimerism induction in mice model.
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چکیده
منابع مشابه
An optimization of protocol for mixed chimerism induction in mice model.
Studies on mixed chimerism are currently focused primarily on obtaining less toxic conditioning protocols. With these issues in mind, we have undertaken the attempt to optimize the procedure of mixed chimerism induction in mice. In order to reduce toxicity, we used decreasing doses of total body irradiation (TBI) together with combination of blocking antibodies. We also tried to eliminate immun...
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Induction of tolerance through mixed chimerism.
"Mixed chimerism" refers to a state in which the lymphohematopoietic system of the recipient of allogeneic hematopoietic stem cells comprises a mixture of host and donor cells. This state is usually attained through either bone marrow or mobilized peripheral blood stem cell transplantation. Although numerous treatment regimens have led to transplantation tolerance in mice, the induction of mixe...
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ژورنال
عنوان ژورنال: Folia Histochemica et Cytobiologica
سال: 2010
ISSN: 1897-5631,0239-8508
DOI: 10.2478/v10042-009-0086-z